• Skinfix Triple Lipid-Peptide Cream Hero Image
  • Triple Lipid Peptide Cream Texture Image
  • Triple Lipid Peptide Cream Action Image
  • Triple Lipid Peptide Cream Refill Action Image
  • Skinfix moisturizer guide showing Triple Lipid-Peptide Cream for dry to normal skin, Ceramide Prime Whipped Cream for normal to combination skin, and Barrier Balancing Water Cream for combination to oily skin.
  • Triple Lipid Peptide Cream New Packaging Image
  • Triple Lipid Peptide Cream Refill Hero Image
  • Triple Lipid Peptide Cream Mini Hero Image
  • Triple Lipid Peptide Cream Jumbo Hero Image
Bestseller

Triple Lipid-Peptide Cream

Re-meet the original formula of this derm-approved must-have.

Most moisturizers mask dryness at skin’s surface. This one—powered by clinically proven ingredients like ceramides and peptides—amplifies your skin’s ability to retain moisture instantly and over time by rebuilding its protective barrier.

Benefits

  • Hydrates
  • Smooths
Size

Get 2 free samples with all orders

Free shipping on orders over $50

Save with Sets

  • Four Skinfix products: Hydrating Foaming Oil Cleanser, Triple Lipid Activating Serum, Brighten + Firm 15% Vitamin C Serum, and Triple Lipid-Peptide Cream.

    The Skinfix Essentials Set

    Four bestsellers. One complete routine.
    $167
    $222 $167
  • Dry-Normal Skin
    Radiance + Repair Duo

    Radiance + Repair Duo

    High-impact dry skin essentials
    5.0
    $105
    $123 $105
  • Exclusively Here
    Skinfix Hydrating Foaming Oil Cleanser, Triple Lipid Activating Serum, Triple Lipid Eye Treatment, and Triple Lipid-Peptide Cream.

    The Fall Ritual Kit

    Barrier care for cooler months
    $155
    $207 $155
  • Dry-Normal Skin
    Skinfix Triple Lipid-Peptide Cream and Triple Lipid Eye Treatment in light blue packaging, on transparent background.

    Hydrate + Tighten Duo

    Anti-aging, hydrating essentials
    5.0
    $92
    $108 $92

Triple Lipid-Peptide Cream

  • Skinfix Triple Lipid-Peptide Cream Hero Image
  • Triple Lipid Peptide Cream Texture Image
  • Triple Lipid Peptide Cream Action Image
  • Triple Lipid Peptide Cream Refill Action Image
  • Skinfix moisturizer guide showing Triple Lipid-Peptide Cream for dry to normal skin, Ceramide Prime Whipped Cream for normal to combination skin, and Barrier Balancing Water Cream for combination to oily skin.
  • Triple Lipid Peptide Cream New Packaging Image
  • Triple Lipid Peptide Cream Refill Hero Image
  • Triple Lipid Peptide Cream Mini Hero Image
  • Triple Lipid Peptide Cream Jumbo Hero Image

Full 1.7 oz

A buttery rich cream that amplifies hydration instantly and over time

A buttery rich cream that amplifies hydration instantly and over time

Woman applying cream to her face with a neutral background
  • Details
    Details
    • Suitable for Sensitive Skin
    • Clinically Tested
    • Dermatologist Tested
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
    Refills

    Restock with a refill pod to save 80% of plastic compared to repurchasing the full size Triple Lipid-Peptide Cream. The refill pod won’t fit the mini 0.5 oz. jar or the XL 3.3 oz. jar.

  • Details
    Details
    • Suitable for Sensitive Skin
    • Clinically Tested
    • Dermatologist Tested
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
    Refills

    Restock with a refill pod to save 80% of plastic compared to repurchasing the full size Triple Lipid-Peptide Cream. The refill pod won’t fit the mini 0.5 oz. jar or the XL 3.3 oz. jar.

  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • Awards
    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

    2025

    Good Housekeeping Beauty Award for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Moisturizer

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

  • Awards
    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

    2025

    Good Housekeeping Beauty Award for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Moisturizer

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

See in Action
  • Before Close-up of a person’s cheek with dotted circles highlighting areas of uneven skin tone and texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.
  • Before Close-up of a person’s cheek with a dotted circle highlighting visible redness and skin texture.
    After Close-up of the same person’s cheek after use, with a dotted circle highlighting changes in the appearance of redness and skin texture.
  • Before Close-up of a person’s cheek with dotted circles highlighting uneven skin tone and skin texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.

Clinical Results

Clinically proven to deliver glowier (+26%), smoother (+29%) and firmer (+12%) skin after 4 weeks
Results of a 4-week clinical trial on 35 subjects, analyzed with expert clinical grading, after 4 weeks

  • 100% showed improved moisture retention, with hydration increasing by 46% immediately and 67% after 4 weeks

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer and corneometer, immediately and after 4 weeks

  • 100% said their skin feels smoother and deeply hydrated

    Results of a 4-week consumer perception study on 35 subjects, after 1 week

  • 100% had immediate barrier function improvement

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer, immediately

Environmental

  • Blue cylindrical container with a lid on a white background
    Jar

    Unscrew the regular size 1.7 oz base and reuse it with the refill, or remove the pump and replace the cap on the base, then place it in the recycle bin. 

    *The refill pod won't fit the mini 0.5 oz jar or the XL 3.3.oz jar. 

    Packaging Facts

    1.7 oz: 70% PCR PP outer Jar. 44% PCR PP by weight inner pod.
    0.5 oz: 50% PCR PP Jar

  • Illustration of Skinfix Triple Lipid-Peptide Cream pump
    Pump

    Save the pump and reuse it with the refill, or place it in the Pact Collective bin for recycling - locations here

    Packaging Facts

    26% PCR mixed material

  • Illustration of Skinfix Triple Lipid-Peptide Cream cap
    Cap

    Save the cap to reuse with the refill component, or snap it back on base to place in the recycle bin

    Packaging Facts

    1.7 oz: 70% PCR 0.5 oz: 50% PCR PP

  • Illustration of Skinfix Triple Lipid-Peptide Cream box
    Box

    Place in recycle bin

    Packaging Facts

    100% FSC certified paper made with 30% recycled fibres and plant-based inks
  • Step 1

    Unscrew pump from jar and remove empty pod–white disc included

  • Step 2

    Open refill pod and remove foil seal

  • Step 3

    Place refill in base jar, screw pump onto base, and prime for use

FAQ

  • Is this safe for sensitive and/or eczema prone skin?

    Yes! Triple Lipid-Peptide Cream is clinically proven to be safe for sensitive skin and is formulated without common irritants, making it a great option for eczema-prone skin too. It’s rich in barrier-supporting ingredients to help keep skin calm, hydrated, and resilient.

  • Is this safe for acne-prone skin?

    Triple Lipid-Peptide Cream was tested to be non-comedogenic and is safe for acne-prone skin. It can be especially helpful if you’re using prescription acne treatments, since it restores the moisture they can deplete. That said, it was developed with dry skin in mind—if you're acne-prone and tend to be more combo or oily, we’d recommend trying our Barrier Balancing Water Cream instead. Water Cream is a better option if you're prone to fungal acne, too.

  • Can I layer this with actives?

    Triple Lipid-Peptide Cream was formulated with hydrating, barrier-supporting ingredients, so it layers well with most actives—including retinoids, vitamin C, AHAs, BHAs and prescription topicals. Its soothing formula can actually help buffer potential irritation, making it a great companion product in your routine. As always, if you’re trying a new combination for the first time, we recommend patch testing or introducing products gradually to see how your skin responds.

  • Is this safe to use during pregnancy and breastfeeding?

    Triple Lipid-Peptide Cream has been reviewed and tested for safety on a panel of people who aren’t pregnant or breastfeeding. It does not include any ingredients known to be unsafe while pregnant or breastfeeding, but as with any new product, we recommend checking with your healthcare provider if you're concerned.

Overall rating: 4.762575 / 5 from 3837 reviews.

AI Generated Review Summary

This Triple Lipid-Peptide Cream is highly regarded for its ability to deeply hydrate and rejuvenate dry skin. Customers praise its quick absorption, rich texture, and the way it leaves skin feeling soft and smooth. The eco-friendly packaging and effective formula are also highlighted as key positives.

Summary topics

  • Absorption Speed (6%): It was observed by customers that this peptide cream absorbs quickly into the skin and leaves the skin hydrated and refreshed.
  • Packaging (7%): Customers raved about the packaging, describing it as eco-friendly, convenient, and environmentally friendly.
  • Effectiveness for Dry Skin (30%): Many customers stated that this cream is perfect for dehydrated and dry skin, providing hydration and rejuvenation.
  • Hydration (7%): Customers keep praising the hydration provided by this product, with many describing it as super hydrating and effective for dry and cracked skin.
  • Texture (7%): It was noted by customers that the texture of the product is rich, creamy, silky, and perfect for winter time.

Review topics: ["color","feels","packaging","issues","husband","skin","texture","scent","looks","hydration","absorbs","shipping","formula","results","ingredients","price","face","improvement","glow","cream","fragrance","container","consistency","moisturizer","amount","irritation","breakouts","refill","pores","residue"].

Review highlights

  • "This cream feels rich and luxurious, yet it absorbs well without leaving my skin greasy." — brandon
  • "Skinfix Triple Lipid-Peptide Cream deeply hydrates, nourishes, provides smoother, radiant and elastic looking skin." — lydiao
  • "It's super hydrating and makes my skin feel so soft and smooth." — eviandoesmakeup

Reviews

Im obsessed with the Triple

"Im obsessed with the Triple Lipid-Peptide Cream, my skin is loving how hydrated it is during the day, I love how juicy and healthy it looks after using your products, I totally recommend this amazing cream"

— Luz S. (5/5)

This is the very best

"This is the very best face cream I’ve ever used! It’s the last thing I put on my face before my sunscreen. My rosacea has improved a lot since adding this plus the Hypochlorous acid. This cream is rich but doesn’t leave me feeling greasy. My skin looks so hydrated as well. It’s also the only, cream my young adult daughter uses on her perioral dermatitis."

— Allison L. (5/5)

I decided to try this

"I decided to try this after using Obagi hydrate for many years. I am loving this triple lipid peptide cream! It's turning out to be a great replacement for that product. There is a nice weight to the cream, not too oily, not watery nor too thick. I'm finding it to be perfect for daily use over my encapsulated retinol product. My skin feels soft, smooth, and looks hydrated. I also like that the delivery system is superior to the Obagii Hydrate in that you can easily get the product out of the container, and you can buy replacement inserts which cuts back on plastic waste."

— Kathy P. (5/5)

This is a great barrier

"This is a great barrier protection moisturizer. I’ve been using it for several years. Skin is a brand that I really really enjoy and I don’t even know why I stopped using them. I’m so happy that I’m back to using it cause my face feels amazing."

— Chylissa B. (5/5)

I'm in my late 60's

"I'm in my late 60's and I've used Skinfix regularly for just about a year. I'm am amazed at the results, not only is my skin softer, my makeup doesn't look like I'm an old lady! That's a bonus! Pricing is so reasonable, especially with the refills. A little goes a long way."

— Vonna M. (5/5)

With fall and winter approaching,

"With fall and winter approaching, this cream has quickly become one of my must haves! It provides the perfect level of rich, lasting hydration without leaving my skin feeling heavy or greasy. My skin feels incredibly soft, smooth, and nourished after using it, and I genuinely believe this is one of the best creams on the market. An absolute standout and one I’ll be reaching for all season long!"

— Kelly B. (5/5)

My holy grail for years!

"My holy grail for years! My sensitive, rosacea, retinol battled complexion loves this moisturizer so much. It wears amazing under makeup! I also love the dispenser and being able to purchase refills to reduce waste."

— Myra M. (5/5)

Great quality

"As always this is the best product I ever tried on my skin, I am so happy to use it, it really change my skin"

— Sofia O. (5/5)

I really love this face

"I really love this face lotion, it just goes on so smoothly, feels so hydrating, it's not sticky or oily. It honestly just feels so so nice. Downfall is definitely price for size of container/ hard to maintain cost."

— Heidi S. (5/5)

It's all about that barrier

"I've been using this product for over 3 years now, and it continues to be my staple daily moisturizer. It is the reason why my skin barrier is always strong even through rough windy cold weather, and why my skin has a nice "juicy" fresh look to it. The real results of this cream occur over time as the ceramide and lipids integrate with your skin and support it. Upon immediate application it feels great, but it is as the weeks and months go by that your skin gradually becomes fortified and even heals from past injury due to inflammation from the compromised barrier it once had."

— Kevin J. (5/5)

Q&A

Is this the original formula?
Hi Veronica, Yes! When we re-launched our barrier+ Triple Lipid Peptide Cream with our patented BL-3 complex, many members from our community voiced that they preferred the original version. After much internal discussion, we've decided to re-launch that original formula, which does not have BL-3 last year in June. All product sold since then is the original formulation. The original offers the same hydration benefits -- it hydrates instantly and over time -- and we're excited to have had the opportunity to hear our community. Please do not hesitate to reach out if you have any other questions, we're here to help! 💙
Is this cream fungal safe?
Hi May, The lipid rich formulation is not fungal acne safe. Our barrier+ Barrier Balancing Water Cream is though!! https://skinfix.com/products/barrier-balancing-water-cream
I'm seeing any peptides listed in the ingredients. What are they called here?
Hi Michelle, Thank you for your question. We list ingredients by their INCI (International Nomenclature of Cosmetic Ingredients) names, which can definitely be a little confusing! Peptides are short chains of amino acids—the building blocks of proteins—and the ones we use in Triple Lipid-Peptide Cream are rice-derived. On the ingredient list, you’ll see them listed as Hydrolyzed Rice Protein. So even though it doesn’t have “peptide” in the name, rest assured it still functions as one in the formula.
Can dry/combo skin use this?
Hi Zion, Absolutely. This was formulated for all skin types as it is non comedogenic. This formula is typically best suited for those with dry/combo skin. It’s designed to absorb well and provide long-lasting hydration, making it a great option for all-day moisture and barrier support. We hope this helps!
If I order this product during the summer, will shipping in the heat or having the box left in a community mailbox in the heat damage the product?
Hi Galus, Thank you for your question- We temperature test all of our products for both extreme cold and heat, to ensure it is stable and able to withstand the many different weather conditions for North America. This should not have any bearing on when you order and how it ships during the summer. If you are concerned, you can also purchase our products at your local Sephora store-we hope this helps!
Does the mini version have a pump like the standard size, or is it just open on top?
Hi Erin, Thank you for reaching out- the mini Triple Lipid-Peptide Cream does not have a pump. It is an open jar to dispense with clean fingers. We hope this helps!
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