• Skinfix Triple Lipid-Peptide Cream Refillable Duo Hero Image
  • Triple Lipid Peptide Cream Texture Image
  • Triple Lipid Peptide Cream Action Image
  • Triple Lipid Peptide Cream Refill Action Image
  • Triple Lipid-Peptide Cream Refillable Duo New Packaging Tile

Triple Lipid-Peptide Cream Refillable Duo

Get double the moisturizer while saving 15%.


This buttery rich moisturizer—powered by clinically proven ingredients like ceramides and peptides—amplifies your skin’s ability to retain moisture instantly and over time by rebuilding its protective barrier. Each time you refill, you use 80% less plastic than if you bought a new jar.

Benefits

  • Hydrates
  • Smooths

Get 2 free samples with all orders

Free shipping on orders over $50

Triple Lipid-Peptide Cream Refillable Duo

  • Skinfix Triple Lipid-Peptide Cream Refillable Duo Hero Image
  • Triple Lipid Peptide Cream Texture Image
  • Triple Lipid Peptide Cream Action Image
  • Triple Lipid Peptide Cream Refill Action Image
  • Triple Lipid-Peptide Cream Refillable Duo New Packaging Tile

A smarter way to stock up—save 15%, use 80% less plastic

A smarter way to stock up—save 15%, use 80% less plastic

Woman applying cream to her face with a neutral background
  • Do No Harm
    What You'll Get
    • Triple Lipid-Peptide Cream Full Size 1.7oz
    • Triple Lipid-Peptide Cream Refill 1.7oz
    Details
    • Clinically Tested
    • Dermatologist Tested
    • Safe for Sensitive Skin
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
  • Do No Harm
    What You'll Get
    • Triple Lipid-Peptide Cream Full Size 1.7oz
    • Triple Lipid-Peptide Cream Refill 1.7oz
    Details
    • Clinically Tested
    • Dermatologist Tested
    • Safe for Sensitive Skin
    • Non-Comedogenic
    • Non-Irritant
    • Hypoallergenic
    • Vegan
    • Cruelty-Free
  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • Ingredients
    3% Triple Lipid Complex

    Ceramides, sterols and fatty acids mimic skin's barrier to lock in moisture

    3% Peptide Solution

    Barrier-repair protein-builders that weightlessly help skin retain moisture

    8% Humectant Blend

    Hyaluronic acid, glycerin, and red algae deposit instant, lasting hydration

    Free From

    × fragrance
    × essential oils
    × silicones
    × phthalates
    × microplastics
    × parabens
    × sulfates
    × PEGs
    × gluten

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • How to Use
    Day + Night
    • Apply 1-2 pumps to clean, dry skin after serum and eye cream
    • Use every day, twice a day—in the morning and at night
    Lock it In

    Apply makeup while moisturizer still feels wet for a boost of dewiness

    Good to Know

    Plays well with actives—like exfoliating acids, retinoids, and brighteners

  • Awards
    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

    2025

    Good Housekeeping Beauty Award for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Actives

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

  • Awards
    2025

    Allure Best of Beauty Award Winner - Best Clean Skincare

    2025

    Good Housekeeping Beauty Award for Genius Anti-Agers

    2024

    WWD - The Greatest Skincare

    2022

    Shape Skin Award

    2022

    Skin Anarchy Top Picks - Actives

    2022

    Prevention Beauty Award Winner - Best Face Moisturizer

    2021

    Women's Health Best of Skincare Award Winner

    2019

    Allure Best of Beauty Award Winner

  • Before Close-up of a person’s cheek with dotted circles highlighting areas of uneven skin tone and texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.
  • Before Close-up of a person’s cheek with a dotted circle highlighting visible redness and skin texture.
    After Close-up of the same person’s cheek after use, with a dotted circle highlighting changes in the appearance of redness and skin texture.
  • Before Close-up of a person’s cheek with dotted circles highlighting uneven skin tone and skin texture.
    After Close-up of the same person’s cheek after use, with dotted circles highlighting changes in the appearance of skin tone and texture.

Clinical Results

Clinically proven to deliver glowier (+26%), smoother (+29%) and firmer (+12%) skin after 4 weeks
Results of a 4-week clinical trial on 35 subjects, analyzed with expert clinical grading, after 4 weeks

  • 100% showed improved moisture retention, with hydration increasing by 46% immediately and 67% after 4 weeks

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer and corneometer, immediately and after 4 weeks

  • 100% said their skin feels smoother and deeply hydrated

    Results of a 4-week consumer perception study on 35 subjects, after 1 week

  • 100% had immediate barrier function improvement

    Results of a 4-week clinical trial on 35 subjects, analyzed with a vapometer, immediately

Environmental

Reducing our impact is important to us

We partnered with Bluebird to complete a full Life Cycle Analysis on the carbon and waste impact of this product.

Reducing our impact is important to us

We partnered with Bluebird to complete a full Life Cycle Analysis on the carbon and waste impact of this product.

Production

Made in North America with ethical labor practices

Box

100% FSC certified paper made with 30% recycled fibres and plant-based inks

Partners
Learn more about our sustainability commitments
  • Illustration of Skinfix Triple Lipid-Peptide Cream pump
    Pump

    Save the pump and reuse it with the refill, or place it in the Pact Collective bin for recycling - locations here

    Packaging Facts

    26% PCR mixed material

  • Illustration of Skinfix Triple Lipid-Peptide Cream cap
    Cap

    Save the cap to reuse with the refill component, or snap it back on base to place in the recycle bin

    Packaging Facts

    1.7 oz: 70% PCR 0.5 oz: 50% PCR PP

  • Blue cylindrical container with a lid on a white background
    Jar

    Unscrew the regular size 1.7 oz base and reuse it with the refill, or remove the pump and replace the cap on the base, then place it in the recycle bin. 

    *The refill pod won't fit the mini 0.5 oz jar or the XL 3.3.oz jar. 

    Packaging Facts

    1.7 oz: 70% PCR PP outer Jar. 44% PCR PP by weight inner pod.
    0.5 oz: 50% PCR PP Jar

  • Jar

    Rinse out excess product and place the pod in the recycle bin

    Packaging Facts

    44% PCR PP Pod. Foil seal

  • Illustration of Skinfix Triple Lipid-Peptide Cream box
    Box

    Place in recycle bin

    Packaging Facts

    100% FSC certified paper made with 30% recycled fibres and plant-based inks
  • Step 1

    Unscrew pump from jar and remove empty pod–white disc included

  • Step 2

    Open refill pod and remove foil seal

  • Step 3

    Place refill in base jar, screw pump onto base, and prime for use

FAQ

  • Is this safe for sensitive and/or eczema prone skin?

    Yes! Triple Lipid-Peptide Cream is clinically proven to be safe for sensitive skin and is formulated without common irritants, making it a great option for eczema-prone skin too. It’s rich in barrier-supporting ingredients to help keep skin calm, hydrated, and resilient.

  • Is this safe for acne-prone skin?

    Triple Lipid-Peptide Cream was tested to be non-comedogenic and is safe for acne-prone skin. It can be especially helpful if you’re using prescription acne treatments, since it restores the moisture they can deplete. That said, it was developed with dry skin in mind—if you're acne-prone and tend to be more combo or oily, we’d recommend trying our Barrier Balancing Water Cream instead. Water Cream is a better option if you're prone to fungal acne, too.

  • Can I layer this with actives?

    Triple Lipid-Peptide Cream was formulated with hydrating, barrier-supporting ingredients, so it layers well with most actives—including retinoids, vitamin C, AHAs, BHAs and prescription topicals. Its soothing formula can actually help buffer potential irritation, making it a great companion product in your routine. As always, if you’re trying a new combination for the first time, we recommend patch testing or introducing products gradually to see how your skin responds.

  • Is this safe to use during pregnancy and breastfeeding?

    Triple Lipid-Peptide Cream has been reviewed and tested for safety on a panel of people who aren’t pregnant or breastfeeding. It does not include any ingredients known to be unsafe while pregnant or breastfeeding, but as with any new product, we recommend checking with your healthcare provider if you're concerned.

Overall rating: 5.0 / 5 from 7 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["moisturizer","cream"].

Review highlights

Reviews

Absolute Favorite

"This works so well with Tretinoin. It keeps my barrier intact, hydrated and I have less peeling. My skin looks so healthy and glows."

— Tonya C. (5/5)

Hydration QUEEN

"This is honestly one of the best moisturizer I've used. It does exactly what is says it will, which is HYDRATE. When we lose hydration we lose our glow and the dry skin is what allows wrinkles and fine lines to creep in. Looking like a grease bomb is a blessing that I took for granted as a teenager. Of course no one wants to walk around looking greasy but that's what keeps us young and glowing, and this cream provides the moisture that my natural skin oil's can't no more. You can always dab some powder on top or use their water moisturizer if this is too much for you, but I'll stick to the OG. I'll take all the moisture I can get. I use it at night and also under my make up, and I consistently get compliments on having nice skin when I'm using it. And that speaks for itself. Do you want nice skin and to prevent wrinkles ? Hydration Hydration Hydration."

— Anna I. (5/5)

Buying Again

"This moisturizer is a lifesaver. I’m buying it again. There was a time that anything that touches my face would burn. The dermatologist prescribed high dose of hydrocortisone cream. This moisturizer was the only thing that kept my skin from getting dried out and inflamed."

— T (5/5)

My favorite!

"I have been using this cream for years now and it is so good for my dry skin! I love that it is refillable and good for the Earth - I just wish there were MORE refillable items at Skinfix or that they could incorporate them into more kits."

— Rebecca (5/5)

Fav moisturizer!

"This is my favorite skinfix product and my holy grail in my routine, especially as someone with dry sensitive skin!"

— Lilly W. (5/5)

the best moisturizer for sensitive skin

"so moisturizing"

— Ashley (5/5)

Most amazing moisturizer!!!

"This moisturizer has totally repaired my skin. My skin barrier was so destroyed from months of inconsistency, cheap skincare fads, and changing hormones. This product has finally brought life back to my skin!!! Also, the smell and feel of it is incredible. This will for sure be my new go-to!"

— Alayna (5/5)

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